3ZKP

Structure of a mutant of P450 EryK in complex with erythromycin B.

Summary for 3ZKP

Entry DOI	10.2210/pdb3zkp/pdb
Descriptor	ERYTHROMYCIN C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE, Erythromycin B, ... (4 entities in total)
Functional Keywords	oxidoreductase-antibiotic complex, catalytic domain, cytochrome p-450 enzyme system, substrate specificity, macrolide antibiotic, oxidoreductase/antibiotic
Biological source	SACCHAROPOLYSPORA ERYTHRAEA NRRL 2338
Total number of polymer chains	1
Total formula weight	46621.33
Authors	Montemiglio, L.C.,Vallone, B.,Savino, C. (deposition date: 2013-01-24, release date: 2013-05-01, Last modification date: 2023-12-20)
Primary citation	Montemiglio, L.C.,Macone, A.,Ardiccioni, C.,Avella, G.,Vallone, B.,Savino, C. Redirecting P450 Eryk Specificity by Rational Site-Directed Mutagenesis. Biochemistry, 52:3678-, 2013 Cited by PubMed: 23597312 DOI: 10.1021/BI400223J PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation