3ZKP

Structure of a mutant of P450 EryK in complex with erythromycin B.

3ZKP の概要

• エントリーDOI: 10.2210/pdb3zkp/pdb
• 分子名称: ERYTHROMYCIN C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE, Erythromycin B, ... (4 entities in total)
• 機能のキーワード: oxidoreductase-antibiotic complex, catalytic domain, cytochrome p-450 enzyme system, substrate specificity, macrolide antibiotic, oxidoreductase/antibiotic
• 由来する生物種: SACCHAROPOLYSPORA ERYTHRAEA NRRL 2338
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46621.33

構造登録者

Montemiglio, L.C.,Vallone, B.,Savino, C. (登録日: 2013-01-24, 公開日: 2013-05-01, 最終更新日: 2023-12-20)

• 主引用文献: Montemiglio, L.C.,Macone, A.,Ardiccioni, C.,Avella, G.,Vallone, B.,Savino, C.; Redirecting P450 Eryk Specificity by Rational Site-Directed Mutagenesis.; Biochemistry, 52:3678-, 2013; PubMed: 23597312; DOI: 10.1021/BI400223J

実験手法

X-RAY DIFFRACTION (2 Å)