3ZJV

Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation

3ZJV の概要

• エントリーDOI: 10.2210/pdb3zjv/pdb
• 関連するPDBエントリー: 3ZJT 3ZJU
• 分子名称: LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR (3 entities in total)
• 機能のキーワード: ligase-rna complex, ligase, protein biosynthesis, class i aminoacyl-trna synthetase, aminoacyl trna synthetase, atp binding, editing synthetase, ligase/rna
• 由来する生物種: ESCHERICHIA COLI; 詳細
• 細胞内の位置: Cytoplasm: P07813
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 127786.71

構造登録者

Cusack, S.,Palencia, A.,Crepin, T.,Hernandez, V.,Akama, T.,Baker, S.J.,Bu, W.,Feng, L.,Freund, Y.R.,Liu, L.,Meewan, M.,Mohan, M.,Mao, W.,Rock, F.L.,Sexton, H.,Sheoran, A.,Zhang, Y.,Zhang, Y.,Zhou, Y.,Nieman, J.A.,Anugula, M.R.,Keramane, E.M.,Savariraj, K.,Reddy, D.S.,Sharma, R.,Subedi, R.,Singh, R.,OLeary, A.,Simon, N.L.,DeMarsh, P.L.,Mushtaq, S.,Warner, M.,Livermore, D.M.,Alley, M.R.K.,Plattner, J.J. (登録日: 2013-01-18, 公開日: 2013-04-17, 最終更新日: 2023-12-20)

• 主引用文献: Hernandez, V.,Crepin, T.,Palencia, A.,Cusack, S.,Akama, T.,Baker, S.J.,Bu, W.,Feng, L.,Freund, Y.R.,Liu, L.,Meewan, M.,Mohan, M.,Mao, W.,Rock, F.L.,Sexton, H.,Sheoran, A.,Zhang, Y.,Zhang, Y.,Zhou, Y.,Nieman, J.A.,Anugula, M.R.,Keramane, E.M.,Savariraj, K.,Reddy, D.S.,Sharma, R.,Subedi, R.,Singh, R.,O'Leary, A.,Simon, N.L.,De Marsh, P.L.,Mushtaq, S.,Warner, M.,Livermore, D.M.,Alley, M.R.K.,Plattner, J.J.; Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.; Antimicrob.Agents Chemother., 57:1394-, 2013; PubMed: 23295920; DOI: 10.1128/AAC.02058-12

実験手法

X-RAY DIFFRACTION (2.31 Å)