3ZJ6
Crystal of Raucaffricine Glucosidase in complex with inhibitor
Summary for 3ZJ6
Entry DOI | 10.2210/pdb3zj6/pdb |
Related | 3ZJ7 3ZJ8 |
Descriptor | RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION, (1R,2S,3S,4R,5R)-4-(cyclohexylmethylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol, ... (4 entities in total) |
Functional Keywords | hydrolase, rg, inhibitor, alkaloid |
Biological source | RAUVOLFIA SERPENTINA (SERPENTWOOD) |
Total number of polymer chains | 2 |
Total formula weight | 122816.86 |
Authors | Xia, L.,Lin, H.,Panjikar, S.,Ruppert, M.,Castiglia, A.,Rajendran, C.,Wang, M.,Schuebel, H.,Warzecha, H.,Jaeger, V.,Stoeckigt, J. (deposition date: 2013-01-17, release date: 2014-01-29, Last modification date: 2023-12-20) |
Primary citation | Xia, L.,Lin, H.,Staniek, A.,Panjikar, S.,Ruppert, M.,Hilgers, P.,Williardt, J.,Rajendran, C.,Wang, M.,Warzecha, H.,Jager, V.,Stockigt, J. Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours. J.Enzyme.Inhib.Med.Chem., 30:472-, 2015 Cited by PubMed: 25140865DOI: 10.3109/14756366.2014.949252 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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