3ZHS

Crystal structure of the SucA domain of Mycobacterium smegmatis KGD, first post-decarboxylation intermediate from alpha-ketoglutarate

Summary for 3ZHS

Entry DOI	10.2210/pdb3zhs/pdb
Related	3ZHQ 3ZHR 3ZHT 3ZHU 3ZHV
Descriptor	MULTIFUNCTIONAL 2-OXOGLUTARATE METABOLISM ENZYME, (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	oxidoreductase, e1o, thiamine diphosphate
Biological source	MYCOBACTERIUM SMEGMATIS
Total number of polymer chains	4
Total formula weight	391033.74
Authors	Wagner, T.,Barilone, N.,Bellinzoni, M.,Alzari, P.M. (deposition date: 2012-12-24, release date: 2013-11-13, Last modification date: 2023-12-20)
Primary citation	Wagner, T.,Barilone, N.,Alzari, P.M.,Bellinzoni, M. A Dual Conformation of the Post-Decarboxylation Intermediate is Associated with Distinct Enzyme States in Mycobacterial Alpha-Ketoglutarate Decarboxylase (Kgd). Biochem.J., 457:425-, 2014 Cited by PubMed: 24171907 DOI: 10.1042/BJ20131142 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation