3X31

Crystal structure of the human vitamin D receptor ligand binding domain complexed with 7,8-cis-14-epi-1a,25-Dihydroxy-19-norvitamin D3

Summary for 3X31

• Entry DOI: 10.2210/pdb3x31/pdb
• Descriptor: Vitamin D3 receptor, (1R,3R,7Z,14beta,17alpha)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-9,10-secoestra-5,7-diene-1,3-diol (3 entities in total)
• Functional Keywords: hormone receptor, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P11473
• Total number of polymer chains: 1
• Total formula weight: 30209.97

Authors

Kakuda, S.,Takimoto-Kamimura, M. (deposition date: 2015-01-13, release date: 2016-01-13, Last modification date: 2024-03-20)

• Primary citation: Sawada, D.,Saito, H.,Kakuda, S.,Takimoto-Kamimura, M.,Matsumoto, Y.,Takagi, K.,Ochiai, E.,Kittaka, A.; Revisiting the 7,8-cis-vitamin D3 derivatives: synthesis, evaluating the biological activity, and study of the binding configuration; To be Published,

Experimental method

X-RAY DIFFRACTION (2.11 Å)