3WTX
Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Summary for 3WTX
Entry DOI | 10.2210/pdb3wtx/pdb |
Related | 3WTS 3WTT 3WTU 3WTV 3WTW 3WTY 3WTZ 3WU0 3WU1 |
Descriptor | Runt-related transcription factor 1, Core-binding factor subunit beta, Protein C-ets-1, ... (6 entities in total) |
Functional Keywords | protein-dna complex, dna-binding, methylation, nucleus, phosphoprotein, transcription regulation, isopeptide bond, proto-oncogene, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus : Q03347 Q08024 Cytoplasm : P14921 |
Total number of polymer chains | 10 |
Total formula weight | 135804.27 |
Authors | Shiina, M.,Hamada, K.,Ogata, K. (deposition date: 2014-04-21, release date: 2014-08-13, Last modification date: 2023-11-08) |
Primary citation | Shiina, M.,Hamada, K.,Inoue-Bungo, T.,Shimamura, M.,Uchiyama, A.,Baba, S.,Sato, K.,Yamamoto, M.,Ogata, K. A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427:1655-1669, 2015 Cited by PubMed: 25083921DOI: 10.1016/j.jmb.2014.07.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report