3WTN

Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Desnitro-imidacloprid

Summary for 3WTN

• Entry DOI: 10.2210/pdb3wtn/pdb
• Related: 2ZJU 2ZJV
• Descriptor: Acetylcholine-binding protein, (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine, CADMIUM ION, ... (5 entities in total)
• Functional Keywords: neonicotinoids, nicotinic acetylcholine receptor, imidacloprid, acetylcholine binding, signaling protein
• Biological source: Lymnaea stagnalis (Great pond snail)
• Cellular location: Secreted: P58154
• Total number of polymer chains: 10
• Total formula weight: 250440.91

Authors

Okajima, T.,Ihara, M.,Yamashita, A.,Oda, T.,Matsuda, K. (deposition date: 2014-04-11, release date: 2015-02-04, Last modification date: 2023-11-08)

• Primary citation: Ihara, M.,Okajima, T.,Yamashita, A.,Oda, T.,Asano, T.,Matsui, M.,Sattelle, D.B.,Matsuda, K.; Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions; Mol.Pharmacol., 86:736-746, 2014; PubMed: 25267717; DOI: 10.1124/mol.114.094698

Experimental method

X-RAY DIFFRACTION (2.09 Å)