Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3WTN

Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Desnitro-imidacloprid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0043083	cellular_component	synaptic cleft
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0043083	cellular_component	synaptic cleft
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0043083	cellular_component	synaptic cleft
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0043083	cellular_component	synaptic cleft
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0043083	cellular_component	synaptic cleft
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0043083	cellular_component	synaptic cleft
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0043083	cellular_component	synaptic cleft
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0043083	cellular_component	synaptic cleft
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0043083	cellular_component	synaptic cleft
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0043083	cellular_component	synaptic cleft

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE N2Y A 301

Chain	Residue
A	TYR89
A	SER142
A	TRP143
A	TYR192
B	TRP53
B	ARG104
B	LEU112

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 302

Chain	Residue
G	ASP2
G	ASP5
A	ASP2
A	ASP5

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 303

Chain	Residue
A	GLU-1
A	HIS69

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 304

Chain	Residue
A	ASP72

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 305

Chain	Residue
A	GLU43
A	ASP129

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 306

Chain	Residue
A	ALA-2
A	HOH535
G	GLU-1

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 307

Chain	Residue
A	HIS69
A	HOH490
G	GLU131

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 308

Chain	Residue
A	ASP129

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 309

Chain	Residue
A	GLU172
A	HOH554

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE N2Y B 301

Chain	Residue
B	TYR89
B	SER142
B	TRP143
B	TYR185
B	CYS187
B	CYS188
B	TYR192
B	HOH410
C	TRP53
C	ARG104
C	LEU112
C	MET114

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD B 302

Chain	Residue
B	ASP2
B	ASP5
F	ASP2
F	ASP5

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD B 303

Chain	Residue
B	GLU-1
B	HIS69

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD B 304

Chain	Residue
B	ASP72
B	NA309

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD B 305

Chain	Residue
B	GLU157
B	ASP161
B	HOH594
C	ASP161
C	NA309
C	HOH450

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 306

Chain	Residue
B	GLU40

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD B 307

Chain	Residue
B	GLU172
B	HOH461

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD B 308

Chain	Residue
B	HOH561
C	GLU172
C	HOH401

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 309

Chain	Residue
B	SER67
B	SER70
B	ASP72
B	CD304
B	HOH514
B	HOH517

site_id	CC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE N2Y C 301

Chain	Residue
C	TYR89
C	SER142
C	TRP143
C	TYR185
C	CYS187
C	TYR192
C	HOH414
D	TRP53
D	ARG104
D	LEU112
D	MET114

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD C 302

Chain	Residue
C	ASP2
C	ASP5
J	ASP2
J	ASP5

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD C 303

Chain	Residue
C	GLU-1
C	HIS69
C	HOH438

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD C 304

Chain	Residue
C	ASP72

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD C 305

Chain	Residue
C	GLU43
C	ASP129

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD C 306

Chain	Residue
B	GLU163
C	GLU163
C	HOH508
C	HOH510

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD C 307

Chain	Residue
C	ALA-2
C	HOH574
J	GLU-1

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD C 308

Chain	Residue
C	GLU157
C	HOH404

site_id	CC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NA C 309

Chain	Residue
C	ASP161
C	HOH424
B	ASP161
B	ASP175
B	CD305
B	HOH594
C	ASN158
C	SER159

site_id	DC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE N2Y D 301

Chain	Residue
D	TYR89
D	SER142
D	TRP143
D	TYR192
E	TRP53
E	ARG104
E	LEU112
E	MET114

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD D 302

Chain	Residue
D	ASP2
D	ASP5
I	ASP2
I	ASP5

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD D 303

Chain	Residue
D	GLU-1
D	HIS69

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD D 304

Chain	Residue
D	GLU196
D	HOH502

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD D 305

Chain	Residue
D	SER151
D	LYS180
D	GLU193
D	HOH402
D	HOH444

site_id	DC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD D 306

Chain	Residue
D	HIS145
D	GLU149
D	HOH524
E	SER75
E	ARG104
E	HOH408

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD D 307

Chain	Residue
D	ALA-2
D	GLU-1
D	HOH522
I	ALA-2

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD D 308

Chain	Residue
E	GLU131

site_id	DC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE N2Y E 301

Chain	Residue
A	TRP53
A	ARG104
A	LEU112
A	MET114
E	TYR89
E	SER142
E	TRP143
E	TYR185
E	CYS187
E	TYR192
E	HOH405

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD E 302

Chain	Residue
E	ASP2
E	ASP5
H	ASP2
H	ASP5

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD E 303

Chain	Residue
E	GLU-1
E	HIS69

site_id	EC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD E 304

Chain	Residue
E	ASP72

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD E 305

Chain	Residue
E	GLU172

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD E 306

Chain	Residue
E	GLU-1
E	HOH521
H	ALA-2

site_id	EC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD E 307

Chain	Residue
A	ARG104
A	HOH496
A	HOH544
E	HIS145
E	GLU149

site_id	EC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE N2Y F 301

Chain	Residue
F	TYR89
F	SER142
F	TRP143
F	TYR185
F	CYS187
F	CYS188
F	TYR192
F	HOH418
G	TRP53
G	ARG104
G	LEU112
G	MET114

site_id	EC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD F 302

Chain	Residue
F	GLU-1
F	HIS69

site_id	EC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD F 303

Chain	Residue
F	LYS179
F	GLU196
F	HOH441

site_id	FC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD F 304

Chain	Residue
F	HIS145
F	GLU149
G	ARG104
G	HOH407
G	HOH482

site_id	FC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD F 305

Chain	Residue
F	SER151
F	LYS180
F	GLU193

site_id	FC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE N2Y G 301

Chain	Residue
G	TYR89
G	SER142
G	TRP143
G	TYR192
H	TRP53
H	ARG104
H	LEU112

site_id	FC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD G 302

Chain	Residue
G	GLU-1
G	HIS69
G	HOH420

site_id	FC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD G 303

Chain	Residue
G	HIS145
G	GLU149
H	ARG104
H	HOH401
H	HOH453

site_id	FC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD G 304

Chain	Residue
G	GLU172

site_id	FC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD G 305

Chain	Residue
G	SER151
G	LYS180
G	GLU193
G	HOH518

site_id	FC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD G 306

Chain	Residue
E	GLU190
G	ASP160

site_id	FC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE N2Y H 301

Chain	Residue
H	TYR89
H	SER142
H	TRP143
H	TYR185
H	CYS187
H	CYS188
H	TYR192
H	HOH415
I	TRP53
I	ARG104
I	LEU112
I	MET114

site_id	GC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD H 302

Chain	Residue
H	GLU-1
H	HIS69
H	HOH469

site_id	GC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD H 303

Chain	Residue
H	ASP72

site_id	GC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE N2Y I 301

Chain	Residue
I	TYR89
I	SER142
I	TRP143
I	THR144
I	CYS188
I	TYR192
J	TRP53
J	LEU102
J	ARG104
J	LEU112
J	MET114

site_id	GC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD I 302

Chain	Residue
C	ARG23
I	GLU-1
I	HIS69

site_id	GC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD I 303

Chain	Residue
I	ASP72

site_id	GC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD I 304

Chain	Residue
B	GLU43
B	ASP129
I	GLU131
I	HOH407

site_id	GC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD I 305

Chain	Residue
B	LYS203
I	GLU43
I	ASP129

site_id	GC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD I 306

Chain	Residue
I	HIS145
I	GLU149
J	SER75
J	ARG104
J	HOH411

site_id	GC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD I 307

Chain	Residue
I	ASP129
I	LYS203

site_id	HC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE N2Y J 301

Chain	Residue
F	TRP53
F	LEU102
F	ARG104
F	LEU112
J	TYR89
J	TRP143
J	CYS187
J	TYR192

site_id	HC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD J 302

Chain	Residue
B	HOH525
J	GLU-1
J	HIS69

site_id	HC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD J 303

Chain	Residue
J	ASP72
J	HOH419

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1030
Details	Domain: {"description":"Ig-like"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	10
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)