3WRO

Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication

3WRO の概要

• エントリーDOI: 10.2210/pdb3wro/pdb
• 関連するPDBエントリー: 3WRN 3WRQ 3WRR 3WRS 4PP4
• 分子名称: Non-capsid protein NS-1, MANGANESE (II) ION (3 entities in total)
• 機能のキーワード: nuclease activity, single and double stranded dna binding, nicking protein, replication
• 由来する生物種: Murine minute virus (MVM)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32398.34

構造登録者

Tewary, S.K.,Zhao, H.,Tang, L. (登録日: 2014-02-27, 公開日: 2015-01-21, 最終更新日: 2024-03-20)

• 主引用文献: Tewary, S.K.,Liang, L.,Lin, Z.,Lynn, A.,Cotmore, S.F.,Tattersall, P.,Zhao, H.,Tang, L.; Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.; Virology, 476C:61-71, 2014; PubMed: 25528417; DOI: 10.1016/j.virol.2014.11.022

実験手法

X-RAY DIFFRACTION (1.48 Å)