3WRO

Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication

Summary for 3WRO

Entry DOI	10.2210/pdb3wro/pdb
Related	3WRN 3WRQ 3WRR 3WRS 4PP4
Descriptor	Non-capsid protein NS-1, MANGANESE (II) ION (3 entities in total)
Functional Keywords	nuclease activity, single and double stranded dna binding, nicking protein, replication
Biological source	Murine minute virus (MVM)
Total number of polymer chains	1
Total formula weight	32398.34
Authors	Tewary, S.K.,Zhao, H.,Tang, L. (deposition date: 2014-02-27, release date: 2015-01-21, Last modification date: 2024-03-20)
Primary citation	Tewary, S.K.,Liang, L.,Lin, Z.,Lynn, A.,Cotmore, S.F.,Tattersall, P.,Zhao, H.,Tang, L. Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding. Virology, 476C:61-71, 2014 Cited by PubMed: 25528417 DOI: 10.1016/j.virol.2014.11.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation