3WNE

Cyclic hexapeptide PKIDNG in complex with HIV-1 integrase

3WNE の概要

• エントリーDOI: 10.2210/pdb3wne/pdb
• 関連するPDBエントリー: 3WNF 3WNG 3WNH
• 関連するBIRD辞書のPRD_ID: PRD_001211
• 分子名称: Gag-Pol polyprotein, LEDGF peptide, CADMIUM ION, ... (6 entities in total)
• 機能のキーワード: dna integration, aids, integrase, endonuclease, polynucleotidyl transferase, dna binding, viral protein, rnaseh, ledgf, lens epithelium derived growth factor, viral protein-peptide complex, viral protein/peptide
• 由来する生物種: Human immunodeficiency virus type 1 (HIV-1); 詳細
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P12497
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 36587.13

構造登録者

Wielens, J.,Chalmers, D.K.,Parker, M.W. (登録日: 2013-12-09, 公開日: 2013-12-25, 最終更新日: 2023-11-08)

• 主引用文献: Northfield, S.E.,Wielens, J.,Headey, S.J.,Mulcair, M.,Scanlon, M.J.,Parker, M.W.,Thompson, P.E.,Chalmers, D.K.; Hexapeptide mimetics of LEDGF in complex with HIV-1 integrase; to be published,

実験手法

X-RAY DIFFRACTION (1.7 Å)