3WKT

Complex structure of an open form of NADPH-cytochrome P450 reductase and heme oxygenase-1

3WKT の概要

• エントリーDOI: 10.2210/pdb3wkt/pdb
• 分子名称: NADPH-cytochrome P450 reductase, Heme oxygenase 1, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: heme degradation, microsomal membrane, oxidoreductase
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• 細胞内の位置: Endoplasmic reticulum membrane ; Single-pass membrane protein ; Cytoplasmic side : P00388; Microsome: P06762
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 206992.77

構造登録者

Sugishima, M.,Sato, H.,Higashimoto, Y.,Harada, J.,Wada, K.,Fukuyama, K.,Noguchi, M. (登録日: 2013-10-31, 公開日: 2014-01-29, 最終更新日: 2023-11-08)

• 主引用文献: Sugishima, M.,Sato, H.,Higashimoto, Y.,Harada, J.,Wada, K.,Fukuyama, K.,Noguchi, M.; Structural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase.; Proc.Natl.Acad.Sci.USA, 111:2524-2529, 2014; PubMed: 24550278; DOI: 10.1073/pnas.1322034111

実験手法

X-RAY DIFFRACTION (4.3 Å)