3WJW

Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-methyl-UMP

Summary for 3WJW

Entry DOI	10.2210/pdb3wjw/pdb
Related	3WJX 3WJY 3WJZ 3WK0 3WK1 3WK2 3WK3
Descriptor	Orotidine 5'-phosphate decarboxylase, 6-methyluridine 5'-(dihydrogen phosphate) (3 entities in total)
Functional Keywords	tim barrel, decarboxylase, pyrimidine biosynthesis, protein-ligand complex, lyase
Biological source	Methanothermobacter thermautotrophicus
Total number of polymer chains	1
Total formula weight	27717.61
Authors	Fujihashi, M.,Kuroda, S.,Pai, E.F.,Miki, K. (deposition date: 2013-10-17, release date: 2013-12-04, Last modification date: 2023-11-08)
Primary citation	Fujihashi, M.,Ishida, T.,Kuroda, S.,Kotra, L.P.,Pai, E.F.,Miki, K. Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J.Am.Chem.Soc., 135:17432-17443, 2013 Cited by PubMed: 24151964 DOI: 10.1021/ja408197k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation