3WJ4

Crystal structure of PPARgamma ligand binding domain in complex with tributyltin

Summary for 3WJ4

• Entry DOI: 10.2210/pdb3wj4/pdb
• Related: 3WJ5
• Descriptor: Peroxisome proliferator-activated receptor gamma, tributylstannanyl (3 entities in total)
• Functional Keywords: protein-ligand complex, dna-binding, metal-binding, nucleus, receptor, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P37231
• Total number of polymer chains: 2
• Total formula weight: 63397.04

Authors

Harada, S.,Hiromori, Y.,Fukakusa, S.,Kawahara, K.,Nakamura, S.,Noda, M.,Uchiyama, S.,Fukui, K.,Nishikawa, J.,Nagase, H.,Kobayashi, Y.,Ohkubo, T.,Yoshida, T.,Nakanishi, T. (deposition date: 2013-10-04, release date: 2014-10-15, Last modification date: 2024-03-20)

• Primary citation: Harada, S.,Hiromori, Y.,Fukakusa, S.,Kawahara, K.,Nakamura, S.,Noda, M.,Uchiyama, S.,Fukui, K.,Nishikawa, J.,Nagase, H.,Kobayashi, Y.,Ohkubo, T.,Yoshida, T.,Nakanishi, T.; Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds; To be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)