3WF4

Crystal structure of human beta-galactosidase mutant I51T in complex with 6S-NBI-DGJ

Summary for 3WF4

• Entry DOI: 10.2210/pdb3wf4/pdb
• Related: 3WEZ 3WF0 3WF1 3WF2 3WF3
• Descriptor: Beta-galactosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: glycosyl hydrolase, tim-barrel domain, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Lysosome. Isoform 2: Cytoplasm, perinuclear region: P16278
• Total number of polymer chains: 4
• Total formula weight: 312412.79

Authors

Suzuki, H.,Ohto, U.,Shimizu, T. (deposition date: 2013-07-16, release date: 2014-04-16, Last modification date: 2023-11-08)

• Primary citation: Suzuki, H.,Ohto, U.,Higaki, K.,Mena-Barragan, T.,Aguilar-Moncayo, M.,Ortiz Mellet, C.,Nanba, E.,Garcia Fernandez, J.M.,Suzuki, Y.,Shimizu, T.; Structural basis of pharmacological chaperoning for human beta-galactosidase; to be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)