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3WEZ

Crystal structure of human beta-galactosidase in complex with NOEV

Summary for 3WEZ
Entry DOI10.2210/pdb3wez/pdb
Related3WF0 3WF1 3WF2 3WF3 3WF4
DescriptorBeta-galactosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (7 entities in total)
Functional Keywordsglycosyl hydrolase, tim-barrel domain, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Lysosome. Isoform 2: Cytoplasm, perinuclear region: P16278
Total number of polymer chains4
Total formula weight312569.14
Authors
Suzuki, H.,Ohto, U.,Shimizu, T. (deposition date: 2013-07-16, release date: 2014-04-23, Last modification date: 2023-11-08)
Primary citationSuzuki, H.,Ohto, U.,Higaki, K.,Mena-Barragan, T.,Aguilar-Moncayo, M.,Ortiz Mellet, C.,Nanba, E.,Garcia Fernandez, J.M.,Suzuki, Y.,Shimizu, T.
Structural basis of pharmacological chaperoning for human beta-galactosidase
to be published,
Experimental method
X-RAY DIFFRACTION (2.11 Å)
Structure validation

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