3WEE
Structure of the full-length yeast Arp7-Arp9 Heterodimer
Summary for 3WEE
| Entry DOI | 10.2210/pdb3wee/pdb |
| Descriptor | Actin-like protein ARP9, Actin-related protein 7, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | actin, chromatin, remodeling, rsc complex, swi-snf complex, nucleus, arp, actin-related protein, actin-like protein, transcription regulator |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
| Total number of polymer chains | 2 |
| Total formula weight | 111006.37 |
| Authors | Lobsiger, J.,Richmond, T.J. (deposition date: 2013-07-06, release date: 2014-02-26, Last modification date: 2024-10-30) |
| Primary citation | Lobsiger, J.,Hunziker, Y.,Richmond, T.J. Structure of the full-length yeast Arp7-Arp9 heterodimer. Acta Crystallogr.,Sect.D, 70:310-316, 2014 Cited by PubMed Abstract: The nuclear actin-related proteins Arp7 and Arp9 are components of the yeast SWI/SNF and RSC chromatin-remodelling complexes. The 3.1 Å resolution crystal structure reported here shows that the full-length Arp7 and Arp9 proteins exist as a dimer without a requirement for additional polypeptides. Of the 11 actin-related proteins, Arp7 and Arp9 are the only two directly demonstrated to form a dimer within this family. The Arp7-Arp9 heterodimer is unlikely to form an actin-like filament based on modelling using the structure. The Arp7-Arp9 structure reveals that its dimerization interface is not altered when bound in a complex with the SWI/SNF Snf2 HSA domain and the regulatory protein Rtt102. PubMed: 24531465DOI: 10.1107/S1399004713027417 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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