3W8D

Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate

Summary for 3W8D

• Entry DOI: 10.2210/pdb3w8d/pdb
• Related: 2YZ7 3VDQ 3VDR 3W8E 3W8F
• Descriptor: D-3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, METHYLMALONIC ACID, ... (6 entities in total)
• Functional Keywords: rossmann fold, oxidreductase, nad+ binding methylmalonate binding, mitochondria, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Alcaligenes faecalis
• Total number of polymer chains: 1
• Total formula weight: 28004.88

Authors

Kanazawa, H.,Tsunoda, M.,Hoque, M.M.,Suzuki, K.,Yamamoto, T.,Takenaka, A. (deposition date: 2013-03-12, release date: 2014-03-12, Last modification date: 2023-11-08)

• Primary citation: Kanazawa, H.,Tsunoda, M.,Hoque, M.M.,Suzuki, K.,Yamamoto, T.,Takenaka, A.; X-ray diffraction of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and methylmalonate; To be Published,

Experimental method

X-RAY DIFFRACTION (1.37 Å)