3W5Q

Crystal structure of complexes of vitamin D receptor ligand binding domain with lithocholic acid derivatives

Summary for 3W5Q

Entry DOI	10.2210/pdb3w5q/pdb
Related	3W5P 3W5R 3W5T
Descriptor	Vitamin D3 receptor, Mediator of RNA polymerase II transcription subunit 1, (5beta,9beta)-3-oxocholan-24-oic acid, ... (4 entities in total)
Functional Keywords	zinc-finger, nuclear receptor-agonist complex, transcription, receptor, transcription regulation, activator, dna-binding, metal-binding, phosphoprotein, nucleus
Biological source	Rattus norvegicus (rat) More
Cellular location	Nucleus: P13053 Q15648
Total number of polymer chains	2
Total formula weight	32540.49
Authors	Masuno, H.,Ikura, T.,Ito, N. (deposition date: 2013-02-05, release date: 2013-06-26, Last modification date: 2024-03-20)
Primary citation	Masuno, H.,Ikura, T.,Morizono, D.,Orita, I.,Yamada, S.,Shimizu, M.,Ito, N. Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives. J.Lipid Res., 54:2206-2213, 2013 Cited by PubMed: 23723390 DOI: 10.1194/jlr.M038307 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation