3W3N
Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 3
3W3N の概要
エントリーDOI | 10.2210/pdb3w3n/pdb |
関連するPDBエントリー | 3W3G 3W3J 3W3K 3W3L 3W3M |
分子名称 | Toll-like receptor 8, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
機能のキーワード | leucine rich repeat, rna, glycosylation, rna recognition, ssrna, receptor, rna receptor, innate immunity, rna binding, secreted, resiquimod, antivirus and antitumor drug, antivirus and antitumor drug binding, immune system |
由来する生物種 | Homo sapiens (human) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 194083.67 |
構造登録者 | |
主引用文献 | Tanji, H.,Ohto, U.,Shibata, T.,Miyake, K.,Shimizu, T. Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands Science, 339:1426-1429, 2013 Cited by PubMed: 23520111DOI: 10.1126/science.1229159 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.1 Å) |
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