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3W1N

Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-iodoorotate

Summary for 3W1N
Entry DOI10.2210/pdb3w1n/pdb
Related3W1A 3W1L 3W1M 3W1P 3W1Q 3W1R
DescriptorDihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, COBALT HEXAMMINE(III), ... (6 entities in total)
Functional Keywordsrossmann fold, oxidoreductase, dihydroorotate/orotate binding, cytosol, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceTrypanosoma cruzi
Cellular locationCytoplasm (By similarity): Q4D3W2
Total number of polymer chains2
Total formula weight70232.74
Authors
Inaoka, D.K.,Iida, M.,Tabuchi, T.,Lee, N.,Matsuoka, S.,Shiba, T.,Sakamoto, K.,Suzuki, S.,Balogun, E.O.,Nara, T.,Aoki, T.,Inoue, M.,Honma, T.,Tanaka, A.,Harada, S.,Kita, K. (deposition date: 2012-11-19, release date: 2013-11-20, Last modification date: 2023-11-08)
Primary citationInaoka, D.K.,Iida, M.,Tabuchi, T.,Lee, N.,Matsuoka, S.,Shiba, T.,Sakamoto, K.,Suzuki, S.,Balogun, E.O.,Nara, T.,Aoki, T.,Inoue, M.,Honma, T.,Tanaka, A.,Harada, S.,Kita, K.
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-iodoorotate
To be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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