3W19

Potent HIV fusion inhibitor CP32M-2

Summary for 3W19

• Entry DOI: 10.2210/pdb3w19/pdb
• Related: 3VGX 3VGY 3VH7
• Descriptor: Transmembrane protein gp41, fusion inhibitor CP32M-2 (3 entities in total)
• Functional Keywords: 6-helix-bundle, mt-hook, inhibit hiv membrane fusion, membrane protein-inhibitor complex, membrane protein/inhibitor
• Biological source: Human immunodeficiency virus type 1 (HIV-1); More
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03375
• Total number of polymer chains: 2
• Total formula weight: 8340.55

Authors

Yao, X.,Waltersperger, S.,Wang, M.T.,Cui, S. (deposition date: 2012-11-13, release date: 2013-12-11, Last modification date: 2023-11-08)

• Primary citation: Yao, X.,Waltersperger, S.,Wang, M.T.,Cui, S.; Optimization of novel anti-HIV fusion inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.278 Å)