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3W0O

Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia, ternary complex with ADP and hygromycin B

Summary for 3W0O
Entry DOI10.2210/pdb3w0o/pdb
Related3W0M 3W0N 3W0P 3W0Q 3W0R 3W0S
DescriptorHygromycin-B 4-O-kinase, ADENOSINE-5'-DIPHOSPHATE, HYGROMYCIN B VARIANT, ... (4 entities in total)
Functional Keywordsphosphotransferase, transferase-antibiotic complex, transferase/antibiotic
Biological sourceEscherichia coli
Total number of polymer chains1
Total formula weight40031.51
Authors
Iino, D.,Takakura, Y.,Fukano, K.,Sasaki, Y.,Hoshino, T.,Ohsawa, K.,Nakamura, A.,Yajima, S. (deposition date: 2012-11-02, release date: 2013-08-07, Last modification date: 2024-03-20)
Primary citationIino, D.,Takakura, Y.,Fukano, K.,Sasaki, Y.,Hoshino, T.,Ohsawa, K.,Nakamura, A.,Yajima, S.
Crystal structures of the ternary complex of APH(4)-Ia/Hph with hygromycin B and an ATP analog using a thermostable mutant.
J.Struct.Biol., 183:76-85, 2013
Cited by
PubMed: 23747390
DOI: 10.1016/j.jsb.2013.05.023
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

217705

数据于2024-03-27公开中

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