3W0M

Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia, apo form

Summary for 3W0M

Entry DOI	10.2210/pdb3w0m/pdb
Related	3W0N 3W0O 3W0P 3W0Q 3W0R 3W0S
Descriptor	Hygromycin-B 4-O-kinase, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	phosphotransferase, transferase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	39194.96
Authors	Iino, D.,Takakura, Y.,Fukano, K.,Sasaki, Y.,Hoshino, T.,Ohsawa, K.,Nakamura, A.,Yajima, S. (deposition date: 2012-11-02, release date: 2013-08-07, Last modification date: 2024-03-20)
Primary citation	Iino, D.,Takakura, Y.,Fukano, K.,Sasaki, Y.,Hoshino, T.,Ohsawa, K.,Nakamura, A.,Yajima, S. Crystal structures of the ternary complex of APH(4)-Ia/Hph with hygromycin B and an ATP analog using a thermostable mutant. J.Struct.Biol., 183:76-85, 2013 Cited by PubMed: 23747390 DOI: 10.1016/j.jsb.2013.05.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation