3VWS

Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-107

Summary for 3VWS

Entry DOI	10.2210/pdb3vws/pdb
Descriptor	Non-structural protein 5, ZINC ION, 5-{[(4-chlorophenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylic acid, ... (5 entities in total)
Functional Keywords	rna-dependent rna polymerase, rna polymerase, viral protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Dengue virus 3
Cellular location	Envelope protein E: Virion membrane; Multi- pass membrane protein: Q6DLV0
Total number of polymer chains	1
Total formula weight	74593.38
Authors	Noble, C.G.,Lescar, J. (deposition date: 2012-08-31, release date: 2013-02-27, Last modification date: 2023-11-08)
Primary citation	Noble, C.G.,Lim, S.P.,Chen, Y.L.,Liew, C.W.,Yap, L.,Lescar, J.,Shi, P.-Y. Conformational flexibility of the Dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor J.Virol., 87:5291-5295, 2013 Cited by PubMed: 23408636 DOI: 10.1128/JVI.00045-13 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation