3VU6
Short peptide HIV entry inhibitor MT-SC22EK with a M-T hook
Summary for 3VU6
Entry DOI | 10.2210/pdb3vu6/pdb |
Related | 1env 3vgx 3VU5 |
Descriptor | Transmembrane protein gp41, MTSC22, SULFATE ION, ... (4 entities in total) |
Functional Keywords | 6-helix bundle, coiled-coil, membrane, fusion inhibitor, m-t hook, hiv entry, membrane protein-inhibitor complex, membrane protein/inhibitor |
Biological source | Human immunodeficiency virus 1 (HIV-1) More |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03375 |
Total number of polymer chains | 2 |
Total formula weight | 7702.92 |
Authors | Yao, X.,Chong, H.H.,Waltersperger, S.,Wang, M.T.,He, Y.X.,Cui, S. (deposition date: 2012-06-19, release date: 2012-12-19, Last modification date: 2023-11-08) |
Primary citation | Chong, H.H.,Yao, X.,Qiu, Z.,Sun, J.,Zhang, M.,Waltersperger, S.,Wang, M.T.,Liu, S.-L.,Cui, S.,He, Y.X. Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1 Faseb J., 27:1203-1213, 2013 Cited by PubMed: 23233535DOI: 10.1096/fj.12-222547 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.324 Å) |
Structure validation
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