3VTK

THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND 5-IODO-DEOXYURIDINE-MONOPHOSPHATE

Summary for 3VTK

• Entry DOI: 10.2210/pdb3vtk/pdb
• Descriptor: THYMIDINE KINASE, ADENOSINE-5'-DIPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: key enzyme in thymidine salvage pathway, additional thymidylate kinase activity, target for anti-herpes viral drugs, transferase
• Biological source: Herpes simplex virus (type 1 / strain F)
• Total number of polymer chains: 1
• Total formula weight: 38066.88

Authors

Wild, K.,Schulz, G.E. (deposition date: 1997-04-01, release date: 1997-10-22, Last modification date: 2024-02-28)

• Primary citation: Wild, K.,Bohner, T.,Folkers, G.,Schulz, G.E.; The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue.; Protein Sci., 6:2097-2106, 1997; PubMed: 9336833

Experimental method

X-RAY DIFFRACTION (3 Å)