3VT4
Crystal structures of rat VDR-LBD with R270L mutation
Summary for 3VT4
Entry DOI | 10.2210/pdb3vt4/pdb |
Related | 2ZLC 3VT3 3VT5 3VT6 3VT7 3VT8 3VT9 |
Descriptor | Vitamin D3 receptor, COACTIVATOR PEPTIDE DRIP, (1R,2Z,3R,5E,7E)-17-{(1S)-1-[(2-ethyl-2-hydroxybutyl)sulfanyl]ethyl}-2-(2-hydroxyethylidene)-9,10-secoestra-5,7,16-triene-1,3-diol, ... (4 entities in total) |
Functional Keywords | transcription, hormone receptor |
Biological source | Rattus norvegicus (rats) More |
Cellular location | Nucleus: P13053 |
Total number of polymer chains | 2 |
Total formula weight | 32598.61 |
Authors | Nakabayashi, M.,Shimizu, M.,Ikura, T.,Ito, N. (deposition date: 2012-05-19, release date: 2013-05-22, Last modification date: 2023-11-08) |
Primary citation | Nakabayashi, M.,Tsukahara, Y.,Iwasaki-Miyamoto, Y.,Mihori-Shimazaki, M.,Yamada, S.,Inaba, S.,Oda, M.,Shimizu, M.,Makishima, M.,Tokiwa, H.,Ikura, T.,Ito, N. Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands. J.Med.Chem., 56:6745-6760, 2013 Cited by PubMed: 23944708DOI: 10.1021/jm400537h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report