3VOL

X-ray Crystal Structure of PAS-HAMP Aer2 in the CN-bound Form

3VOL の概要

• エントリーDOI: 10.2210/pdb3vol/pdb
• 分子名称: Aerotaxis transducer Aer2, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ... (4 entities in total)
• 機能のキーワード: heme, oxygen sensor protein, pas, hamp, cyanomet, cn-bound, signaling protein
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26442.43

構造登録者

Sawai, H.,Sugimoto, H.,Shiro, Y.,Aono, S. (登録日: 2012-01-27, 公開日: 2012-05-23, 最終更新日: 2024-03-20)

主引用文献

Sawai, H.,Sugimoto, H.,Shiro, Y.,Ishikawa, H.,Mizutani, Y.,Aono, S.
Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginosa
Chem.Commun.(Camb.), 48:6523-6525, 2012

PubMed Abstract: The crystal structure of a truncated Aer2, a signal transducer protein from Pseudomonas aeruginosa, consisting of the heme-containing PAS and di-HAMP domains revealed that a distal tryptophan residue (Trp283) plays an important role in stabilizing the heme-bound O(2) and intra-molecular signal transduction upon O(2) binding.

PubMed: 22622145
DOI: 10.1039/c2cc32549g

実験手法

X-RAY DIFFRACTION (2.399 Å)