3VNN

Crystal Structure of a sub-domain of the nucleotidyltransferase (adenylation) domain of human DNA ligase IV

Summary for 3VNN

Entry DOI	10.2210/pdb3vnn/pdb
Related	1IK9 1X9N 2E2W 3II6 3L2P
Descriptor	DNA ligase 4 (2 entities in total)
Functional Keywords	dna ligase, non-homologous end joining, dna repair, xrcc4, ligase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P49917
Total number of polymer chains	1
Total formula weight	16196.51
Authors	Ochi, T.,Wu, Q.,Chirgadze, D.Y.,Grossmann, J.G.,Bolanos-Garcia, V.M.,Blundell, T.L. (deposition date: 2012-01-17, release date: 2012-06-20, Last modification date: 2024-03-20)
Primary citation	Ochi, T.,Wu, Q.,Chirgadze, D.Y.,Grossmann, J.G.,Bolanos-Garcia, V.M.,Blundell, T.L. Structural insights into the role of domain flexibility in human DNA ligase IV Structure, 20:1212-1222, 2012 Cited by PubMed: 22658747 DOI: 10.1016/j.str.2012.04.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.903 Å)

Structure validation