3VIU の概要
エントリーDOI | 10.2210/pdb3viu/pdb |
分子名称 | Phosphoribosylformylglycinamidine synthase 2, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (6 entities in total) |
機能のキーワード | structural genomics, riken structural genomics/proteomics initiative, rsgi, ligase, purine metabolism, atp-binding |
由来する生物種 | Thermus thermophilus |
細胞内の位置 | Cytoplasm (By similarity): Q5SMH8 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 80003.41 |
構造登録者 | Suzuki, S.,Yanai, H.,Kanagawa, M.,Tamura, S.,Watanabe, Y.,Fuse, K.,Baba, S.,Sampei, G.,Kawai, G.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2011-10-12, 公開日: 2012-01-18, 最終更新日: 2024-10-30) |
主引用文献 | Suzuki, S.,Yanai, H.,Kanagawa, M.,Tamura, S.,Watanabe, Y.,Fuse, K.,Baba, S.,Sampei, G.,Kawai, G. Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8 Acta Crystallogr.,Sect.F, 68:14-19, 2012 Cited by PubMed Abstract: The crystal structure of PurL from Thermus thermophilus HB8 (TtPurL; TTHA1519) was determined in complex with an adenine nucleotide, PO(4)(3-) and Mg(2+) at 2.35 Å resolution. TtPurL consists of 29 α-helices and 28 β-strands, and one loop is disordered. TtPurL consists of four domains, A1, A2, B1 and B2, and the structures of the A1-B1 and A2-B2 domains were almost identical to each other. Although the sequence identity between TtPurL and PurL from Thermotoga maritima (TmPurL) is higher than that between TtPurL and the PurL domain of the large PurL from Salmonella typhimurium (StPurL), the secondary structure of TtPurL is much more similar to that of StPurL than to that of TmPurL. PubMed: 22232163DOI: 10.1107/S1744309111048184 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.35 Å) |
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