3VI2

Crystal Structure Analysis of Plasmodium falciparum OMP Decarboxylase in complex with inhibitor HMOA

3VI2 の概要

• エントリーDOI: 10.2210/pdb3vi2/pdb
• 分子名称: Orotidine 5'-phosphate decarboxylase, 4-(2-hydroxy-4-methoxyphenyl)-4-oxobutanoic acid, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: orotidine 5 f-monophosphate decarboxylase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Plasmodium falciparum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76249.88

構造登録者

Takashima, Y.,Mizohata, E.,Krungkrai, S.R.,Matsumura, H.,Krungkrai, J.,Horii, T.,Inoue, T. (登録日: 2011-09-16, 公開日: 2012-08-01, 最終更新日: 2024-03-20)

• 主引用文献: Takashima, Y.,Mizohata, E.,Krungkrai, S.R.,Fukunishi, Y.,Kinoshita, T.,Sakata, T.,Matsumura, H.,Krungkrai, J.,Horii, T.,Inoue, T.; The in silico screening and X-ray structure analysis of the inhibitor complex of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase; J.Biochem., 152:133-138, 2012; PubMed: 22740703; DOI: 10.1093/jb/mvs070

実験手法

X-RAY DIFFRACTION (2.1 Å)