3VC2

Crystal structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor A3(2) in complex with Mg2+, geranyl diphosphate, and S-adenosyl-L-homocysteine

Summary for 3VC2

• Entry DOI: 10.2210/pdb3vc2/pdb
• Related: 3VC1
• Descriptor: Geranyl diphosphate 2-C-methyltransferase, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total)
• Functional Keywords: rossmann fold, methyltransferase fold, sam-dependent methyltransferase, c-methyltransferase, terpenoid biosynthesis, 2-methylisoborneol biosynthesis, transferase
• Biological source: Streptomyces coelicolor
• Total number of polymer chains: 12
• Total formula weight: 426544.13

Authors

Koksal, M.,Christianson, D.W. (deposition date: 2012-01-03, release date: 2012-04-11, Last modification date: 2023-09-13)

• Primary citation: Koksal, M.,Chou, W.K.,Cane, D.E.,Christianson, D.W.; Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification.; Biochemistry, 51:3003-3010, 2012; PubMed: 22455498; DOI: 10.1021/bi300109c

Experimental method

X-RAY DIFFRACTION (2.046 Å)