3VC2

Crystal structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor A3(2) in complex with Mg2+, geranyl diphosphate, and S-adenosyl-L-homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Geranyl diphosphate 2-C-methyltransferase	polymer	312	35040.1	12	UniProt (Q9F1Y5) Pfam (PF08241)	Streptomyces coelicolor	GPP methyltransferase
2	CA, M, R, Y (J, A, D, H)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	BA, DA, FA, GA, N... (I, J, K, L, A...)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	12	Chemie (SAH)
4	AA, EA, O, T (H, J, A, D)	GERANYL DIPHOSPHATE	non-polymer		314.2	4	Chemie (GPP)
5	V (E)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	HA, IA, JA, KA, LA... (A, B, C, D, E...)	water	water		18.0	1165	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 292 (UniProt: Q9F1Y5)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	420481.1
Non-Polymers*	Number of molecules	21
	Total formula weight	6063.1
All*	Total formula weight	426544.1

*Water molecules are not included.