3V8D

Crystal structure of human CYP7A1 in complex with 7-ketocholesterol

3V8D の概要

• エントリーDOI: 10.2210/pdb3v8d/pdb
• 分子名称: Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, (3beta,8alpha,9beta)-3-hydroxycholest-5-en-7-one, ... (6 entities in total)
• 機能のキーワード: cytochrome, oxidoreductase, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein: P22680
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115574.30

構造登録者

Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Usanov, S.A.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2011-12-22, 公開日: 2013-01-09, 最終更新日: 2023-09-13)

• 主引用文献: Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Usanov, S.A.,Park, H.; Crystal structure of human CYP7A1 in complex with 7-ketocholesterol; To be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)