3V7D

Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex

Summary for 3V7D

Entry DOI	10.2210/pdb3v7d/pdb
Related	1NEX 3MKS
Descriptor	Suppressor of kinetochore protein 1, Cell division control protein 4, Protein SIC1, ... (4 entities in total)
Functional Keywords	wd 40 domain, phospho-peptide complex, e3 ubiquitin ligase, ligase, cell cycle, phospho binding protein, sic1, phosphorylation
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Total number of polymer chains	5
Total formula weight	147054.61
Authors	Tang, X.,Orlicky, S.,Mittag, T.,Csizmok, V.,Pawson, T.,Forman-Kay, J.,Sicheri, F.,Tyers, M. (deposition date: 2011-12-20, release date: 2012-05-02, Last modification date: 2023-09-13)
Primary citation	Tang, X.,Orlicky, S.,Mittag, T.,Csizmok, V.,Pawson, T.,Forman-Kay, J.D.,Sicheri, F.,Tyers, M. Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 109:3287-3292, 2012 Cited by PubMed: 22328159 DOI: 10.1073/pnas.1116455109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.306 Å)

Structure validation