3V5G
Crystal structure of human carbonic anhydrase II in complex with the 4-sulfamido-benzenesulfonamide inhibitor
Summary for 3V5G
| Entry DOI | 10.2210/pdb3v5g/pdb |
| Related | 1CA2 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (6 entities in total) |
| Functional Keywords | lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 30768.73 |
| Authors | D'Ambrosio, K.,De Simone, G. (deposition date: 2011-12-16, release date: 2012-07-25, Last modification date: 2023-09-13) |
| Primary citation | D'Ambrosio, K.,Smaine, F.Z.,Carta, F.,De Simone, G.,Winum, J.Y.,Supuran, C.T. Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups. J.Med.Chem., 55:6776-6783, 2012 Cited by PubMed: 22775345DOI: 10.1021/jm300818k PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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