3V2Y

Crystal Structure of a Lipid G protein-Coupled Receptor at 2.80A

Summary for 3V2Y

• Entry DOI: 10.2210/pdb3v2y/pdb
• Related: 3v2w
• Descriptor: Sphingosine 1-phosphate receptor 1, Lysozyme chimera (E.C.3.2.1.17), {(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl}phosphonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sphingosine, edg receptor, lipid receptor, multiple sclerosis, autoimmunity, structural genomics, psi-biology, gpcr network, gpcr, membrane protein, g protein coupled receptor, membrane, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 59536.75

Authors

Hanson, M.A.,Roth, C.B.,Jo, E.,Griffith, M.T.,Scott, F.L.,Reinhart, G.,Desale, H.,Clemons, B.,Cahalan, S.M.,Schuerer, S.C.,Sanna, M.G.,Han, G.W.,Kuhn, P.,Rosen, H.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2011-12-12, release date: 2012-02-15, Last modification date: 2024-04-03)

• Primary citation: Hanson, M.A.,Roth, C.B.,Jo, E.,Griffith, M.T.,Scott, F.L.,Reinhart, G.,Desale, H.,Clemons, B.,Cahalan, S.M.,Schuerer, S.C.,Sanna, M.G.,Han, G.W.,Kuhn, P.,Rosen, H.,Stevens, R.C.; Crystal structure of a lipid G protein-coupled receptor.; Science, 335:851-855, 2012; PubMed: 22344443; DOI: 10.1126/science.1215904

Experimental method

X-RAY DIFFRACTION (2.8 Å)