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3V2O

Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2

Summary for 3V2O
Entry DOI10.2210/pdb3v2o/pdb
Related3SO8 3V2X 3V30 3V31
DescriptorAnkyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2 (3 entities in total)
Functional Keywordsstructural genomics consortium, sgc, ankra2, ank repeat, protein binding, lrp2/megalin
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm, cytoskeleton : Q9H9E1
Apical cell membrane ; Single- pass type I membrane protein : P98158
Total number of polymer chains2
Total formula weight22370.35
Authors
Lam, R.,Xu, C.,Bian, C.B.,Kania, J.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-12, release date: 2012-04-04, Last modification date: 2023-09-13)
Primary citationXu, C.,Jin, J.,Bian, C.,Lam, R.,Tian, R.,Weist, R.,You, L.,Nie, J.,Bochkarev, A.,Tempel, W.,Tan, C.S.,Wasney, G.A.,Vedadi, M.,Gish, G.D.,Arrowsmith, C.H.,Pawson, T.,Yang, X.J.,Min, J.
Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5:ra39-ra39, 2012
Cited by
PubMed: 22649097
DOI: 10.1126/scisignal.2002979
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.89 Å)
Structure validation

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