3V1S

Scaffold tailoring by a newly detected Pictet-Spenglerase ac-tivity of strictosidine synthase (STR1): from the common tryp-toline skeleton to the rare piperazino-indole framework

3V1S の概要

• エントリーDOI: 10.2210/pdb3v1s/pdb
• 分子名称: Strictosidine synthase, 2-(1H-indol-1-yl)ethanamine (3 entities in total)
• 機能のキーワード: strictosidine synthase, alkaloid biosynthesis, strictosidine synthase family, lyase
• 由来する生物種: Rauvolfia serpentina (devilpepper)
• 細胞内の位置: Vacuole: P68175
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71852.31

構造登録者

Wu, F.,Zhu, H.,Sun, L.,Rajendran, C.,Wang, M.,Ren, X.,Panjikar, S.,Cherkasov, A.,Zou, H.,Stoeckigt, J. (登録日: 2011-12-10, 公開日: 2012-02-29, 最終更新日: 2023-11-08)

• 主引用文献: Wu, F.,Zhu, H.,Sun, L.,Rajendran, C.,Wang, M.,Ren, X.,Panjikar, S.,Cherkasov, A.,Zou, H.,Stockigt, J.; Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework; J.Am.Chem.Soc., 134:1498-1500, 2012; PubMed: 22229634; DOI: 10.1021/ja211524d

実験手法

X-RAY DIFFRACTION (2.328 Å)