3UVJ
Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.
Summary for 3UVJ
Entry DOI | 10.2210/pdb3uvj/pdb |
Related | 2WZ1 |
Descriptor | Guanylate cyclase soluble subunit alpha-3, Guanylate cyclase soluble subunit beta-1, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | nitric oxide, structural genomics, structural genomics consortium, sgc, cgmp biosynthesis, gtp binding metal-binding, nucleotide-binding, cystol, lyase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q02108 Q02153 |
Total number of polymer chains | 4 |
Total formula weight | 99557.96 |
Authors | Allerston, C.K.,Berridge, G.,Chalk, R.,Cooper, C.D.O.,Savitsky, P.,Vollmar, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,von Delft, F.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2011-11-30, release date: 2011-12-28, Last modification date: 2024-02-28) |
Primary citation | Allerston, C.K.,von Delft, F.,Gileadi, O. Crystal structures of the catalytic domain of human soluble guanylate cyclase. Plos One, 8:e57644-e57644, 2013 Cited by PubMed: 23505436DOI: 10.1371/journal.pone.0057644 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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