3UP1

Crystal structure of the unliganded human interleukin-7 receptor extracellular domain

3UP1 の概要

• エントリーDOI: 10.2210/pdb3up1/pdb
• 分子名称: Interleukin-7 receptor subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose, ... (7 entities in total)
• 機能のキーワード: cytokine receptor, fibronectin type 3 fold, membrane and soluble, glycosylation, immune system
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53629.05

構造登録者

McElroy, C.A.,Holland, P.J.,Walsh, S.T.R. (登録日: 2011-11-17, 公開日: 2012-02-08, 最終更新日: 2022-12-21)

• 主引用文献: McElroy, C.A.,Holland, P.J.,Zhao, P.,Lim, J.M.,Wells, L.,Eisenstein, E.,Walsh, S.T.; Structural reorganization of the interleukin-7 signaling complex.; Proc.Natl.Acad.Sci.USA, 109:2503-2508, 2012; PubMed: 22308406; DOI: 10.1073/pnas.1116582109

実験手法

X-RAY DIFFRACTION (2.15 Å)