3UEN

Crystal structure of TopBP1 BRCT4/5 domains

Summary for 3UEN

• Entry DOI: 10.2210/pdb3uen/pdb
• Related: 3UEO
• Descriptor: DNA topoisomerase 2-binding protein 1, THIOCYANATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: brct domain, phospho-peptide binding, peptide binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q92547
• Total number of polymer chains: 1
• Total formula weight: 22756.92

Authors

Leung, C.C.,Glover, J.N.M. (deposition date: 2011-10-31, release date: 2013-07-03, Last modification date: 2024-02-28)

• Primary citation: Leung, C.C.,Sun, L.,Gong, Z.,Burkat, M.,Edwards, R.,Assmus, M.,Chen, J.,Glover, J.N.; Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.; Structure, 21:1450-1459, 2013; PubMed: 23891287; DOI: 10.1016/j.str.2013.06.015

Experimental method

X-RAY DIFFRACTION (1.9 Å)