3U82

Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion

Summary for 3U82

• Entry DOI: 10.2210/pdb3u82/pdb
• Related: 2C36 3ALP 3U83
• Descriptor: Envelope glycoprotein D, Poliovirus receptor-related protein 1 (2 entities in total)
• Functional Keywords: hsv-1 gd, nectin-1, binding mode, nectin-1 dimerization preclusion, viral protein-cell adhesion complex, viral protein/cell adhesion
• Biological source: Human herpesvirus 1 (HHV-1); More
• Cellular location: Virion membrane; Single-pass type I membrane protein (By similarity): Q69091; Isoform Alpha: Cell membrane; Single-pass type I membrane protein. Isoform Delta: Cell membrane; Single-pass type I membrane protein. Isoform Gamma: Secreted: Q15223
• Total number of polymer chains: 2
• Total formula weight: 67970.74

Authors

Zhang, N.,Yan, J.,Lu, G.,Guo, Z.,Fan, Z.,Wang, J.,Shi, Y.,Qi, J.,Gao, G.F. (deposition date: 2011-10-15, release date: 2012-03-21, Last modification date: 2023-11-01)

• Primary citation: Zhang, N.,Yan, J.,Lu, G.,Guo, Z.,Fan, Z.,Wang, J.,Shi, Y.,Qi, J.,Gao, G.F.; Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.; Nat Commun, 2:577-577, 2011; PubMed: 22146396; DOI: 10.1038/ncomms1571

Experimental method

X-RAY DIFFRACTION (3.164 Å)