3U81
Crystal structure of a SAH-bound semi-holo form of rat Catechol-O-methyltransferase
Summary for 3U81
Entry DOI | 10.2210/pdb3u81/pdb |
Related | 3nwb 3nwe 3r6t 3s68 |
Descriptor | Catechol O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, POTASSIUM ION, ... (4 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Rattus norvegicus (rat) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 25117.84 |
Authors | Ehler, A.,Schlatter, D.,Stihle, M.,Benz, J.,Rudolph, M.G. (deposition date: 2011-10-15, release date: 2012-02-01, Last modification date: 2024-02-28) |
Primary citation | Ellermann, M.,Lerner, C.,Burgy, G.,Ehler, A.,Bissantz, C.,Jakob-Roetne, R.,Paulini, R.,Allemann, O.,Tissot, H.,Grunstein, D.,Stihle, M.,Diederich, F.,Rudolph, M.G. Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors. Acta Crystallogr.,Sect.D, 68:253-260, 2012 Cited by PubMed: 22349227DOI: 10.1107/S0907444912001138 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.13 Å) |
Structure validation
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