3U67

Crystal structure of the N-terminal domain of Hsp90 from Leishmania major(LmjF33.0312)in complex with ADP

Summary for 3U67

• Entry DOI: 10.2210/pdb3u67/pdb
• Related: 3h80
• Descriptor: Heat shock protein 83-1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, atpase, chaperone, atp binding
• Biological source: Leishmania major
• Total number of polymer chains: 1
• Total formula weight: 26748.18

Authors

Pizarro, J.C.,Wernimont, A.K.,Hutchinson, A.,Mackenzie, F.,Fairlamb, A.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Ferguson, M.A.J.,Hui, R.,Hills, T.,Structural Genomics Consortium (SGC) (deposition date: 2011-10-12, release date: 2012-05-30, Last modification date: 2023-09-13)

• Primary citation: Pizarro, J.C.,Hills, T.,Senisterra, G.,Wernimont, A.K.,Mackenzie, C.,Norcross, N.R.,Ferguson, M.A.,Wyatt, P.G.,Gilbert, I.H.,Hui, R.; Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.; PLoS Negl Trop Dis, 7:e2492-e2492, 2013; PubMed: 24147171; DOI: 10.1371/journal.pntd.0002492

Experimental method

X-RAY DIFFRACTION (1.77 Å)