3U4U
Casein kinase 2 in complex with AZ-Inhibitor
Summary for 3U4U
Entry DOI | 10.2210/pdb3u4u/pdb |
Descriptor | Casein kinase II subunit alpha, 3-{5-(acetylamino)-3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1H-indol-1-yl}propanoic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | kinase, transferase, inhibitor binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40357.41 |
Authors | Larsen, N.A.,Dowling, J. (deposition date: 2011-10-10, release date: 2012-08-22, Last modification date: 2024-02-28) |
Primary citation | Dowling, J.E.,Chuaqui, C.,Pontz, T.W.,Lyne, P.D.,Larsen, N.A.,Block, M.H.,Chen, H.,Su, N.,Wu, A.,Russell, D.,Pollard, H.,Lee, J.W.,Peng, B.,Thakur, K.,Ye, Q.,Zhang, T.,Brassil, P.,Racicot, V.,Bao, L.,Denz, C.R.,Cooke, E. Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization. ACS Med Chem Lett, 3:278-283, 2012 Cited by PubMed: 24900464DOI: 10.1021/ml200257n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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