3TZ3
Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 2
Summary for 3TZ3
Entry DOI | 10.2210/pdb3tz3/pdb |
Descriptor | Acetyl-CoA carboxylase, 6-{[1-(anthracen-9-ylcarbonyl)piperidin-4-yl]methyl}-2-methylquinoline (3 entities in total) |
Functional Keywords | carboxyltransferase, ligase |
Biological source | Saccharomyces cerevisiae S288c (Baker's yeast) |
Cellular location | Cytoplasm: Q00955 |
Total number of polymer chains | 3 |
Total formula weight | 262996.23 |
Authors | Rajamohan, F.,Marr, E.,Reyes, A.,Landro, J.A.,Anderson, M.D.,Corbett, J.W.,Dirico, K.J.,Harwood, J.H.,Tu, M.,Vajdos, F.F. (deposition date: 2011-09-26, release date: 2011-10-19, Last modification date: 2023-09-13) |
Primary citation | Rajamohan, F.,Marr, E.,Reyes, A.R.,Landro, J.A.,Anderson, M.D.,Corbett, J.W.,Dirico, K.J.,Harwood, J.H.,Tu, M.,Vajdos, F.F. Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion. J.Biol.Chem., 286:41510-41519, 2011 Cited by PubMed: 21953464DOI: 10.1074/jbc.M111.275396 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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