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3TWW

Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human LNPEP (chimeric peptide)

Summary for 3TWW
Entry DOI10.2210/pdb3tww/pdb
Related3TWQ 3TWR 3TWS 3TWT 3TWU 3TWV 3TWX
DescriptorTankyrase-2, human LNPEP, SULFATE ION, ... (4 entities in total)
Functional Keywordsankyrin repeat, protein-protein interaction, substrate recruitment, poly(adp-ribosyl)ation, signaling protein-peptide complex, signaling protein/peptide
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: Q9H2K2
Total number of polymer chains4
Total formula weight39604.57
Authors
Guettler, S.,Sicheri, F. (deposition date: 2011-09-22, release date: 2011-12-07, Last modification date: 2011-12-28)
Primary citationGuettler, S.,Larose, J.,Petsalaki, E.,Gish, G.,Scotter, A.,Pawson, T.,Rottapel, R.,Sicheri, F.
Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147:1340-1354, 2011
Cited by
PubMed: 22153077
DOI: 10.1016/j.cell.2011.10.046
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

건을2024-03-27부터공개중

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